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As we’ve seen with COVID-19, the response speed of supply chains is critical in helping slow down and even prevent the total number of casualties in a global health emergency. The sooner solutions can be assembled — whether it is a hospital being built or getting PPE into the hands of medical teams — the sooner people can be treated and the less spread that occurs...A model simulation cited in Nature shows that, “…if China had implemented its control measures a week earlier, it could have prevented 67 percent of all cases in the country. Implementing the measures three weeks earlier...would have cut the number of infections to 5 percent of the total.” Similarly, Italian officials estimate that if they had acted 10 days sooner, they could have avoided tens of thousands of fatalities. Supply chains play an important role in implementing response measures and building out a local healthcare system’s capacity...READ MORE

As global demand intensifies for an old malaria drug that some believe can combat Covid-19, a distributor that supplies the key active pharmaceutical ingredient to compound pharmacies in the U.S. has raised prices by huge amounts over the past week...Spectrum Chemical boosted the wholesale price for a 100-gram container of hydroxychloroquine sulfate by about 350%, to approximately $1,160, while a 1,000-gram container jumped 230% to $5,932. And the price for a 5,000 gram container roughly tripled to almost $30,000...Spectrum explained the sudden clamor for the drug has made it more difficult to obtain the active ingredient, sometimes causing its own suppliers to ship partially filled orders or cancel them outright...READ MORE

Pfizer, AbbVie, Novartis and other pharma companies are pledging millions in COVID-19 relief funds to help healthcare workers, patients and communities...Pfizer announced $40 million in both cash and grants for medical and community needs in the U.S. and around the world. In the U.S., emergency relief funds will go to government public health organizations and nonprofit community health organizations, while grants will be awarded to community health clinics for immediate and long-term needs of healthcare workers involved the COVID-19 response. Pfizer, along with Eli Lilly and Merck, previously announced a program to allow employees with medical and lab expertise to volunteer with local healthcare systems...AbbVie pledged $35 million in a COVID-19 relief package—its largest disaster donation to date—and encouraged other companies follow suit...READ MORE

Hospitals in Nevada are still not near their maximum capacity as the number of confirmed cases of the novel coronavirus grow, though Southern Nevada hospitals appear to be experiencing the most strain so far, according to a Nevada Hospital Association report shared with government officials...The data...shows that Southern Nevada hospitals have a higher percentage of occupied beds, occupied ICU beds and ventilators in use than their counterparts in northern and rural Nevada. In Southern Nevada, 65 percent of hospital beds are occupied, 79 percent of ICU beds are occupied and 56 percent of ventilators are in use, compared to 57 percent occupied beds, 43 percent occupied ICU beds and 30 percent of ventilators in use in Washoe County...READ MORE

...the Centers for Medicare & Medicaid Services recently released their new projections for U.S. National Health Expenditures. Unfortunately, the coronavirus almost immediately made these predictions obsolete...It’s still useful to analyze these forecasts for a pre-pandemic examination of U.S. healthcare spending. A few highlights of the 2024 outlook: READ MORE

• Total U.S. spending on healthcare was projected to grow, from $3.6 trillion in 2018 to $5.0 trillion in 2024.
• Spending on hospitals and professional services was expected to grow by a combined $800 billion—more than 60% of CMS’s projected $1.4 trillion increase in U.S. healthcare spending. That’s consistent with historical trends.
• Net spending on outpatient prescription drugs in 2024 was projected to shrink to less than 9% of total U.S. spending. That would be its lowest level since 2000.

This week, the top managed care news includes a report on how CDC lacks data to tell the full story on disparities in the COVID-19 pandemic, Medicare Advantage gets a pay bump amid COVID-19 rule changes, and the nation’s top infectious disease expert speaks with the editor-in-chief of JAMA.

A coalition of national and local pharmacy organizations is praising the Department of Health and Human Services’ decision to allow licensed pharmacists to order and administer COVID-19 tests during the new coronavirus disease pandemic...“The accessibility and distribution of retail and independent community-based pharmacies make pharmacists the first point of contact with a healthcare professional for many Americans,” said HHS Assistant Secretary for Health Brett P. Giroir, MD...“This will further expand testing for Americans, particularly our healthcare workers and first responders who are working around the clock to provide care, compassion and safety to others.”...READ MORE

...in the letter, Abramowitz explained that, although ASHP is grateful for the action the Administration has taken to provide hospitals with necessary personal protective equipment and ventilators, they “will be rendered useless without an adequate supply of the medications…that must administered concomitantly with mechanical ventilation in critically ill patients…to ensure the successful use of this life-saving supportive care.”...Medications used in conjunction with ventilator include opioids, sedatives, and paralytics...This week, the Drug Enforcement Administration announced it will take additional steps to allow for the increased production of controlled substances used in COVID-19 care...READ MORE

The continued prosperity of a biopharma company is dependent on its ability to keep churning out breakthrough new drugs and turning them into commercial successes backed by a growing body of clinical evidence. Which shops are doing best on those terms?...IDEA Pharma has ranked AstraZeneca at the top of the pharma invention scale—awarding it "best pipeline" honors—and crowned Roche king in the land of innovation...READ MORE

Mylan is one of a group of drugmakers that have joined the global effort to supply doses of generic hydroxychloroquine, an antimalarial touted as a possible COVID-19 therapy, to ongoing clinical trials. Now, after ramping up production, Mylan is ready to dole out its stockpile faster than expected...After announcing last month it would restart production of hydroxychloroquine to meet global demand, Mylan plans to donate millions of doses of the drug "ahead of schedule,"...Mylan will give away 10 million hydroxychloroquine tablets to the U.S. Department of Health and Human Services to supplement investigational trials for COVID-19 and bolster the FDA's emergency use program...READ MORE