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Pfizer has been accused of bullying governments in Latin America over coronavirus disease 2019 vaccine negotiations, a recent investigative article revealed...The accusations involve the company’s requests that some countries establish sovereign assets as a guarantee against the costs associated with future legal suits made on behalf of citizens who experience an adverse event after the shot...The story, published in The Bureau of Investigative Journalism, states that demands made by the global pharmaceutical giant Pfizer resulted in a three-month delay in a vaccine deal for one country. In the case of Argentina and Brazil, the countries made no national deals with the company...READ MORE

Rich countries are on course to have over a billion more doses of COVID-19 vaccines than they need, leaving poorer nations scrambling for leftover supplies as the world seeks to curb the coronavirus pandemic...In an analysis of current supply deals for COVID-19 vaccines, the ONE Campaign said wealthy countries, such as the United States and Britain, should share the excess doses to “supercharge” a fully global response to the pandemic...the United States, the European Union, Britain, Australia, Canada and Japan have already secured more than 3 billion doses - over a billion more than the 2.06 billion needed to give their entire populations two doses...READ MORE

A federal judge has dismissed a lawsuit filed by several hospital groups seeking to get the Department of Health and Human Services to clamp down on drugmakers restricting access to products...Federal Judge Yvonne Gonzalez Rogers issued a ruling...that hospitals had to use a new dispute resolution process to settle the feud with the drugmakers, which the hospitals cannot sue individually under federal law for 340B violations...READ MORE

The World Health Organization has granted an emergency authorization to AstraZeneca’s coronavirus vaccine, a move that should allow the U.N. agency’s partners to ship millions of doses to countries worldwide as part of a U.N.-backed program to tame the pandemic...the WHO said it was clearing the AstraZeneca vaccines made by the Serum Institute of India and South Korea’s AstraZeneca-SKBio...“Countries with no access to vaccines to date will finally be able to start vaccinating their health workers and populations at risk,” said Dr Mariângela Simão, the WHO’s Assistant-Director General for Access to Medicines and Health Products....READ MORE

The uncertainty of coronavirus disease 2019 caused anticipatory purchasing of medications around the world, driving demand to an unprecedented high. Meanwhile, drug factories shut down in order to prevent the spread of COVID-19, the drug-supply chain was disrupted, and drug shortages resulted. In the face of these drug shortages, pharmacy personnel responded by initiating local policy changes, implementing detailed antibiotic stewardship, and enacting quantity limits for in-demand medications...READ MORE

Almost two-thirds of Americans now give the pharma industry a thumbs up. It’s a stunning reversal from just one year ago when only about one-third (32%) rated the industry positively, according to The Harris Poll surveys...In its most recent February poll, 62% rated the pharma industry as a 5, 6 or 7 on a 7-point scale, with 1 equating to “very bad” and 7 to “very good.” That’s an increase of 30 percentage points since January 2020, before the pandemic hit U.S. shores...And that's a key point: The hockey-stick upturn stems directly from pharma's proactive response to COVID-19...READ MORE

Nearly 82% of hospitals surveyed by the Joint Commission in 2019 were noncompliant with at least one Medication Management chapter item. Still, experts say they are hopeful that recent revisions will help those hospitals meet the accreditor’s expectations...Topping the list of noncompliance in 2019 was the medication administration standard, which 49% of hospitals failed to adhere to, Mansur noted. “Surveyors have been finding medications being administered for an indication when another medication was specified, or an ordered medication given for a different indication, and often this is done without a documented explanation,” she said. “Surveyors will also often see that administration of medication, particularly titration medication, is performed differently than is directed by the order.”...READ MORE

Health authorities in some European countries are facing resistance to AstraZeneca’s COVID-19 vaccine after side-effects led hospital staff and other front-line workers to call in sick, putting extra strain on already-stretched services...Such symptoms, as reported in clinical trials for the AstraZeneca shot, can include a high temperature or headache and are a normal sign that the body is generating an immune response. They usually fade within a day or so...But with the AstraZeneca shot the latest to be rolled out, health authorities in France have issued guidance to stagger giving the shot, two regions in Sweden paused vaccinations, and in Germany some essential workers are refusing it...READ MORE

Pfizer Inc and BioNTech SE have asked the U.S. health regulator to relax requirements for their COVID-19 vaccine to be stored at ultra-low temperatures, potentially allowing it to be kept in pharmacy freezers...Approval by the Food and Drug Administration could send a strong signal to other regulators around the world that may ease distribution of the shot in lower-income countries...The companies have submitted new temperature data to the FDA to support an update to the current label that would allow vials to be stored at -25 to -15 degrees Celsius (-13°F to 5°F) for a total of two weeks...READ MORE

Preventing medication errors is an essential component of caring for patients and must be a core mission of every pharmacy. For medication error–prevention efforts to be effective, they must be a priority...The information in the tables of this review summarizes many of the significant error-prevention strategies recommended in the ISMP Medication Safety Alert! Acute Care newsletter from January through December 2020...READ MORE

Table 1. Safety Issues Related to Labeling, Packaging, and Nomenclature
Auxiliary label obscures critical reconstitution information on label of REVATIO (sildenafil; Pfizer) oral suspension carton

Table 2. Safety Issues Associated With Order Communication and Documentation
Confusion between LYUMJEV and HUMALOG (both insulin lispro by Lilly), which have different onsets of action

Table 3. Problems Involving Drug Information, Patient Information, Patient Education, and Staff Education
Administer adenosine rapidly for cardioversion

Table 4. Safety Issues Related to Medical Devices and Equipment
Bypassing soft low-dose alerts for subtherapeutic heparin infusions

Table 5. Other Discussion Items
Differences between human error, at-risk behavior, and reckless behavior

Table 6. ISMP’s Targeted Medication Safety Best Practices for Hospitals
FDA removes syringe administration from vinCRIStine labeling