Author: Peter

All-party parliamentary group recommends community pharmacy play a bigger role in the NHS to take pressure off Gps...Giving all community pharmacists the opportunity to become prescribers by 2022 and introducing a minor ailment service throughout England are among a series of recommendations made in a report by the All-Party Pharmacy Group, following an investigation into the impact of government reforms...The APPG, which is made up of a cross section of MPs with an interest in pharmacy, has also called on NHS England to outline their strategy for implementing the recommendations of the Murray Review into "community pharmacy clinical services"…Community pharmacy is a highly valued, but an underutilised resource, the APPG said, and the profession needs to play a more integrated role in both primary care services, and the treatment of patients with long-term health conditions...The health service is facing huge challenges due to patient demand, and by working to develop services, community pharmacy can shoulder some of the burden facing GPs, and other parts of the NHS...

PBMs occupy a key crossroads of the health system, acting as a nexus among insurers, employers and drug companies. Through a complex web of agreements they help decide what drugs are covered by a patient’s insurance, and how much they’ll cost at the pharmacy counter. The problem, say critics, is that opacity makes it hard for employers to know how much the PBM is paying and profiting on each transaction -- an impression reinforced by restrictions on who can audit them and how.

• Swelling Costs - President Donald Trump has repeatedly complained about high drug prices
• Wrangling Rebates - The most carefully guarded secrets of the PBM industry involve tens of billions of dollars in rebates they collect from drug companies. Those payments help drugmakers secure favorable spots on medication menus that PBMs offer to millions of patients.
• Other Avenues - Rebates are only one way drugmakers pass money to PBMs. Others include fees for care management, administration and inventory procurement.

...Johnson & Johnson said...the U.S. Justice Department has opened an investigation concerning management and advisory services provided to rheumatology and gastroenterology practices that bought two of its drugs...The...company said its Janssen Biotech Inc unit received a civil investigative demand from the Justice Department regarding an investigation under the False Claims Act related to its arthritis drugs Remicade and Simponi Aria...U.S. Attorney's Office...is seeking documents broadly relating to pharmaceutical co-payment support programs for hepatitis C drug Olysiotm, Simponi and Crohn's disease drug Stelara… also seeks documents relating to average manufacturer price and best price reporting to the Center for Medicare and Medicaid services related to those products...

A debate has emerged over the future of the standalone pharmacy benefit manager, putting Express Scripts at the center of an intensifying discussion over how best to manage drug costs for consumers, employers and the government...Pharmacy benefit managers are middlemen between drug makers and consumers when it comes to purchasing drugs and providing prescription coverage...PBM’s role has come under scrutiny lately as high priced drugs bust employer and government budgets for prescriptions. Critics are questioning whether PBMs operate in a transparent way and therefore don’t pass along all of the savings they can to consumers...insurers are closing ranks around a model that brings the PBM closer to the health insurer. UnitedHealth Group owns OptumRx, a rapidly growing PBM and Anthem is seeking requests for proposals from PBMs for a new contract that would begin in 2020. Anthem's current contract with Express Scripts runs out at the end of 2019...Express Scripts, however, says it has a track record of saving Anthem and its employer clients money and is committed to the standalone model...

Sticker shock over $89,000 muscular-dystrophy treatment from Marathon Pharmaceuticals and shame campaign against CEO led to hasty sale...Entrepreneur Jeffrey Aronin said a few years ago he hoped to eventually sell Marathon Pharmaceuticals LLC, which he controls and runs, for billions of dollars...Some employees have said they now expect him to shut down the company...His deflated ambition is a sign of the increasingly hostile reaction to drug companies that specialize in sharply raising the prices of old medications. Mr. Aronin did that over and over again for 15 years, most recently after Marathon won approval in February to sell a drug for muscular dystrophy in the U.S...It took only a month for sticker shock to cascade into criticism from families of patients with Duchenne muscular dystrophy...a shame campaign from congressional lawmakers in both parties and then a surprise deal by Marathon to sell the treatment to another company...It’s too soon to tell if Marathon’s fast retreat has damaged the long-term viability of the business model of sharply raising the prices of drugs. Other companies that have used a similar strategy include Valeant Pharmaceuticals International Inc. and Horizon Pharma PLC...Mr. Aronin seemed to have concluded that the negative publicity was insurmountable. He decided to sell despite reservations from a Marathon executive who favored trying to ride out the controversy...The Emflaza sale was completed in April. Marathon got $140 million in cash and stock, plus more than 20% of the drug’s future sales and a potential $50 million payment.

I (Adam Fein) had the privilege of meeting with Secretary of Health and Human Services Tom Price. I was invited to meet with Secretary Price for one of his listening sessions with industry experts and stakeholders. I appreciated the opportunity to share my perspectives...In our meeting, I highlighted four ways that the 340B Drug Pricing Program is raising drug costs. I then offered eight specific recommendations for improving the program by addressing the widespread channel distortions the program has caused.

HOW 340B RAISES DRUG COSTS

1. Encouraging a shift in site of care from lower-cost physician offices to higher-cost hospital outpatient settings.
2. Reducing manufacturers’ rebates to Medicare Part D and commercial payers.
3. Raising out-of-pocket costs for uninsured patients.
4. Reducing the generic dispensing rate and slowing the adoption of biosimilars.

HOW TO ADDRESS CHANNEL DISTORTIONS FROM THE 340B DRUG PRICING PROGRAM

1. Require that covered entities share financial savings from the 340B program with uninsured and vulnerable patients.
2. Revise hospital eligibility for the 340B program to create a clearer patient definition.
3. Remove incentives for extraordinary hospital profits and site-of-care consolidations.
4. Require HRSA and Apexus (the Prime Vendor) to report the size and scope of the 340B program.
5. Mandate that contract pharmacies for 340B hospitals charge no more than the discounted 340B price to uninsured, underinsured, and vulnerable patients.
6. Require contract pharmacies to identify 340B prescriptions at the time of adjudication (payer prescription approval).
7. Require the disclosure of and transparency into the fees and profits generated by 340B contract pharmacies.
8. Limit the number and geographic scope of contract pharmacy arrangements.

The World Health Organization is to launch a pilot project this year to assess cheap copies of expensive biotech cancer drugs in a bid to make such medicines more widely available in poorer countries...The U.N. agency said...it would invite drugmakers in September to submit applications for pre-qualification of so-called biosimilar versions of two such drugs on its essential medicines list, Roche's Rituxan (rituximab) and Herceptin (trastuzumab)...The move is a boost for biosimilars which are expected to account for a growing proportion of treatments, particularly for cancer, as patents on the original branded products expire...The WHO plays a critical role in monitoring drug quality in poorer countries through its pre-qualification program, which ensures that treatments supplied by U.N. agencies such as UNICEF are of acceptable quality...

Aetna said...that it won't sell individual coverage next year in its two remaining states - Nebraska and Delaware - after projecting a $200 million loss this year. It had already dropped Iowa and Virginia for next year. The insurer once sold the coverage in 15 states, but slashed that to four after losing about $450 million in 2016...The government-backed marketplaces are a pillar of the Obama-era federal law because they allow millions of people to buy health insurance with help from income-based tax credits. But insurers like Humana, and now Aetna, have been fleeing that market, and the remaining coverage options are growing thin…

In the last couple of weeks we’ve seen a number of articles in the press describing the Cancer Drugs Fund a ‘tragedy for patients’ and a ‘waste of money’...​​​In part, this has been sparked by a recently published academic study that also claimed that several the medicines on the fund did not add value to patients – even suggesting that some did more harm than good...Sensationalist headlines about the cost of medicines are rarely a fair reflection of reality…Several of these medicines had been approved early by regulators, who decided that there was an urgency in getting them to the patients who needed them...there was little real world data available on these medicines at the time...The fact is it takes time, even after regulatory approval, to gather longer-term data to form a complete picture of the value of any medicine– the longer a medicine keeps someone alive the longer it takes to collect overall survival data...The trouble is we were – and for the most part still are – pretty far from having a perfect evidence-based way of allocating resources across the NHS…

Nevada lands at the bottom of a list, this time ranking the best and worst states for children’s health care...The state finished No. 51 in research by WalletHub, a credit services website. The findings continue a long, depressing tradition for Nevada, which is no stranger to performing poorly in measures of health. However, valley health care professionals say they’re optimistic that medical services for kids are improving in the state, even if it’s happening more slowly than anybody would like...Experts say Nevada’s challenges range from a relative dearth of pediatricians and family care physicians to a transience among residents that can make obtaining regular preventive care for kids a back-burner task...Nevada has the fewest number of physicians per capita in the United States...This has posed a significant challenge to our community in having access to care or preventive care...As a result, the emergency rooms in Las Vegas as well as the state serve in many ways as the sole access to care...So patients utilize emergency rooms for nonemergent care and to receive care that they’d normally receive in a pediatrician’s office or an internist’s office...